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Synthesis, Structural Characterization, and Preclinical Efficacy of a Novel Paclitaxel-Loaded Alginate Nanoparticle for Breast Cancer Treatment

Purpose. The antitumor activity of a novel alginate (ALG) polymer-based particle that contained paclitaxel (PTX) was evaluated using human primary breast cancer cells. Materials and Methods. PTX was combined with ALG in a nanoparticle as a drug delivery system designed to improve breast cancer tumor...

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Detalles Bibliográficos
Autores principales: Markeb, Ahmed A., El-Maali, Nagwa A., Sayed, Douaa M., Osama, Amany, Abdel-Malek, Mohamed A. Y., Zaki, Amen H., Elwanis, Mostafa E. A., Driscoll, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021896/
https://www.ncbi.nlm.nih.gov/pubmed/27660726
http://dx.doi.org/10.1155/2016/7549372