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Skin scarification with Plasmodium falciparum peptide vaccine using synthetic TLR agonists as adjuvants elicits malaria sporozoite neutralizing immunity

Malaria eradication will require a combination of vector control, chemotherapy and an easily administered vaccine. Sterile immunity can be elicited in humans by immunization with sporozoites, the infective stage injected by bite of the mosquito vector, however, whole parasite vaccines present formid...

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Detalles Bibliográficos
Autores principales: Mitchell, Robert A., Altszuler, Rita, Frevert, Ute, Nardin, Elizabeth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021941/
https://www.ncbi.nlm.nih.gov/pubmed/27624667
http://dx.doi.org/10.1038/srep32575