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Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as monomers and dimers, and mediates its function by binding glycosaminoglycans (GAG) and CXCR2 receptor. We recently s...

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Detalles Bibliográficos
Autores principales: Sawant, Kirti V., Poluri, Krishna Mohan, Dutta, Amit K., Sepuru, Krishna Mohan, Troshkina, Anna, Garofalo, Roberto P., Rajarathnam, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021969/
https://www.ncbi.nlm.nih.gov/pubmed/27625115
http://dx.doi.org/10.1038/srep33123