Cargando…

Chemokine CXCL1 mediated neutrophil recruitment: Role of glycosaminoglycan interactions

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as monomers and dimers, and mediates its function by binding glycosaminoglycans (GAG) and CXCR2 receptor. We recently s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sawant, Kirti V., Poluri, Krishna Mohan, Dutta, Amit K., Sepuru, Krishna Mohan, Troshkina, Anna, Garofalo, Roberto P., Rajarathnam, Krishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021969/ https://www.ncbi.nlm.nih.gov/pubmed/27625115 http://dx.doi.org/10.1038/srep33123

Ejemplares similares

Platelet-Derived Chemokine CXCL7 Dimer Preferentially Exists in the Glycosaminoglycan-Bound Form: Implications for Neutrophil–Platelet Crosstalk
por: Brown, Aaron J., et al.
Publicado: (2017)

Solution Structure of CXCL5 — A Novel Chemokine and Adipokine Implicated in Inflammation and Obesity
por: Sepuru, Krishna Mohan, et al.
Publicado: (2014)

Structural Basis of Native CXCL7 Monomer Binding to CXCR2 Receptor N-Domain and Glycosaminoglycan Heparin
por: Brown, Aaron J., et al.
Publicado: (2017)

Chemokine CXCL7 Heterodimers: Structural Insights, CXCR2 Receptor Function, and Glycosaminoglycan Interactions
por: Brown, Aaron J., et al.
Publicado: (2017)

Lysines and Arginines play non-redundant roles in mediating chemokine-glycosaminoglycan interactions
por: Joseph, Prem Raj B., et al.
Publicado: (2018)

Flexible Linker Modulates Glycosaminoglycan Affinity of Decorin Binding Protein A
por: Morgan, Ashli, et al.
Publicado: (2015)

Heparin-bound chemokine CXCL8 monomer and dimer are impaired for CXCR1 and CXCR2 activation: implications for gradients and neutrophil trafficking
por: Joseph, Prem Raj B., et al.
Publicado: (2017)

Long-Range Coupled Motions Underlie Ligand Recognition by a Chemokine Receptor
por: Sepuru, Krishna Mohan, et al.
Publicado: (2020)

Monomeric and Dimeric CXCL8 Are Both Essential for In Vivo Neutrophil Recruitment
por: Das, Sandhya Thulasi, et al.
Publicado: (2010)

Mechanistic insights into molecular evolution of species-specific differential glycosaminoglycan binding surfaces in growth-related oncogene chemokines
por: Gulati, Khushboo, et al.
Publicado: (2017)

Solution NMR characterization of chemokine CXCL8/IL-8 monomer and dimer binding to glycosaminoglycans: structural plasticity mediates differential binding interactions
por: Joseph, Prem Raj B., et al.
Publicado: (2015)

Nitration of chemokine CXCL8 acts as a natural mechanism to limit acute inflammation
por: Thompson, Sarah, et al.
Publicado: (2023)

Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational Nitration
por: Thompson, Sarah, et al.
Publicado: (2017)

Elucidating the Molecular Interactions of Chemokine CCL2 Orthologs with Flavonoid Baicalin
por: Joshi, Nidhi, et al.
Publicado: (2020)

Hydroxyl Groups on Annular Ring-B Dictate the Affinities of Flavonol–CCL2 Chemokine Binding Interactions
por: Joshi, Nidhi, et al.
Publicado: (2021)

Structural Insights Into How Proteoglycans Determine Chemokine-CXCR1/CXCR2 Interactions: Progress and Challenges
por: Rajarathnam, Krishna, et al.
Publicado: (2020)

CXCL17 binds efficaciously to glycosaminoglycans with the potential to modulate chemokine signaling
por: Giblin, Sean P., et al.
Publicado: (2023)

Ehrlichia chaffeensis TRP120 nucleomodulin binds DNA with disordered tandem repeat domain
por: Klema, Valerie J., et al.
Publicado: (2018)

Chemokines and Glycosaminoglycans
por: Proudfoot, Amanda E. I.
Publicado: (2015)

Protein engineering techniques: gateways to synthetic protein universe
por: Poluri, Krishna Mohan, et al.
Publicado: (2017)

Editorial: Bacteriophages Isolation From the Environment and Their Antimicrobial Therapeutic Potential, Volume 2
por: Poluri, Krishna Mohan, et al.
Publicado: (2022)

Elucidating the Eradication Mechanism of Perillyl Alcohol against Candida glabrata Biofilms: Insights into the Synergistic Effect with Azole Drugs
por: Gupta, Payal, et al.
Publicado: (2021)

Interference with Glycosaminoglycan-Chemokine Interactions with a Probe to Alter Leukocyte Recruitment and Inflammation In Vivo
por: Li, Sandra, et al.
Publicado: (2014)

Diverging Mechanisms of Activation of Chemokine Receptors Revealed by Novel Chemokine Agonists
por: Sarmiento, Jose, et al.
Publicado: (2011)

Editorial: Bacteriophages Isolation From the Environment and Their Antimicrobial Therapeutic Potential
por: Poluri, Krishna Mohan, et al.
Publicado: (2021)

Correction: Diverging Mechanisms of Activation of Chemokine Receptors Revealed by Novel Chemokine Agonists
por: Sarmiento, Jose, et al.
Publicado: (2012)

Dynamics-Derived Insights into Complex Formation between the CXCL8 Monomer and CXCR1 N-Terminal Domain: An NMR Study
por: Joseph, Prem Raj B., et al.
Publicado: (2018)

Targeting Chemokine—Glycosaminoglycan Interactions to Inhibit Inflammation
por: Crijns, Helena, et al.
Publicado: (2020)

Perspectives on the Biological Role of Chemokine:Glycosaminoglycan Interactions
por: Handel, Tracy M., et al.
Publicado: (2020)

CXCL9-Derived Peptides Differentially Inhibit Neutrophil Migration In Vivo through Interference with Glycosaminoglycan Interactions
por: Vanheule, Vincent, et al.
Publicado: (2017)

A Requirement for Neutrophil Glycosaminoglycans in Chemokine:Receptor Interactions Is Revealed by the Streptococcal Protease SpyCEP
por: Goldblatt, Jennifer, et al.
Publicado: (2019)

Molecular investigations on Candida glabrata clinical isolates for pharmacological targeting
por: Gupta, Hrishikesh, et al.
Publicado: (2022)

Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System
por: Proudfoot, Amanda E. I., et al.
Publicado: (2017)

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states
por: Madalli, Shimona, et al.
Publicado: (2015)

Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells
por: Koch, Christian, et al.
Publicado: (2022)

The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan Interactions
por: Dyer, Douglas P., et al.
Publicado: (2016)

Sensing the Messenger: Potential Roles of Cyclic-di-GMP in Rickettsial Pathogenesis
por: Narra, Hema P., et al.
Publicado: (2022)

Conserved Apical Proline Regulating the Structure and DNA Binding Properties of Helicobacter pylori Histone-like DNA Binding Protein (Hup)
por: Agarwal, Nipanshu, et al.
Publicado: (2022)

Glycosaminoglycan-Mediated Downstream Signaling of CXCL8 Binding to Endothelial Cells
por: Derler, Rupert, et al.
Publicado: (2017)

Correction: Interactions of the chemokines CXCL11 and CXCL12 in human tumor cells
por: Koch, Christian, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_pomb0sbo7mherg8983dn115ahl