An APOC3 3′UTR variant associated with plasma triglycerides levels and coronary heart disease by creating a functional miR-4271 binding site

Apolipoprotein C-III (APOC3) is a key regulator of plasma triglycerides levels. Increasing evidence has shown that loss-of-function mutations in APOC3 is associated with reduction in plasma triglycerides levels and will confer a benefit in patients at high risk for cardiovascular disease. However, t...

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Detalles Bibliográficos
Autores principales: Hu, Sen-Lin, Cui, Guang-Lin, Huang, Jin, Jiang, Jian-Gang, Wang, Dao-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021972/
https://www.ncbi.nlm.nih.gov/pubmed/27624799
http://dx.doi.org/10.1038/srep32700

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021972/
https://www.ncbi.nlm.nih.gov/pubmed/27624799
http://dx.doi.org/10.1038/srep32700

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