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Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!

It has become clear that mitochondrial reactive oxygen species (mtROS) are not simply villains and mitochondria the hapless targets of their attacks. Rather, it appears that mitochondrial dysfunction itself and the signaling function of mtROS can have positive effects on lifespan, helping to extend...

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Detalles Bibliográficos
Autores principales: Hekimi, Siegfried, Wang, Ying, Noë, Alycia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021979/
https://www.ncbi.nlm.nih.gov/pubmed/27683586
http://dx.doi.org/10.3389/fgene.2016.00161