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Comparative analysis of linker histone H1, MeCP2, and HMGD1 on nucleosome stability and target site accessibility

Chromatin architectural proteins (CAPs) bind the entry/exit DNA of nucleosomes and linker DNA to form higher order chromatin structures with distinct transcriptional outcomes. How CAPs mediate nucleosome dynamics is not well understood. We hypothesize that CAPs regulate DNA target site accessibility...

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Detalles Bibliográficos
Autores principales: Riedmann, Caitlyn, Fondufe-Mittendorf, Yvonne N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021983/
https://www.ncbi.nlm.nih.gov/pubmed/27624769
http://dx.doi.org/10.1038/srep33186