NOX2 amplifies acetaldehyde-mediated cardiomyocyte mitochondrial dysfunction in alcoholic cardiomyopathy

Alcoholic cardiomyopathy (ACM) resulting from excess alcohol consumption is an important cause of heart failure (HF). Although it is assumed that the cardiotoxicity of the ethanol (EtOH)-metabolite acetaldehyde (ACA) is central for its development and progression, the exact mechanisms remain obscure...

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Detalles Bibliográficos
Autores principales: Brandt, Moritz, Garlapati, Venkata, Oelze, Matthias, Sotiriou, Efthymios, Knorr, Maike, Kröller-Schön, Swenja, Kossmann, Sabine, Schönfelder, Tanja, Morawietz, Henning, Schulz, Eberhard, Schultheiss, Heinz-Peter, Daiber, Andreas, Münzel, Thomas, Wenzel, Philip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021994/
https://www.ncbi.nlm.nih.gov/pubmed/27624556
http://dx.doi.org/10.1038/srep32554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021994/
https://www.ncbi.nlm.nih.gov/pubmed/27624556
http://dx.doi.org/10.1038/srep32554

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