P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons

Plasticity at excitatory synapses can be induced either by synaptic release of glutamate or the release of gliotransmitters such as ATP. Recently, we showed that postsynaptic P2X2 receptors activated by ATP released from astrocytes downregulate synaptic AMPAR, providing a novel mechanism by which gl...

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Detalles Bibliográficos
Autores principales: Pougnet, Johan-Till, Compans, Benjamin, Martinez, Audrey, Choquet, Daniel, Hosy, Eric, Boué-Grabot, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022001/
https://www.ncbi.nlm.nih.gov/pubmed/27624155
http://dx.doi.org/10.1038/srep31836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022001/
https://www.ncbi.nlm.nih.gov/pubmed/27624155
http://dx.doi.org/10.1038/srep31836

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