MDM2 promoter SNP55 (rs2870820) affects risk of colon cancer but not breast-, lung-, or prostate cancer

Two functional SNPs (SNP285G > C; rs117039649 and SNP309T > G; rs2279744) have previously been reported to modulate Sp1 transcription factor binding to the promoter of the proto-oncogene MDM2, and to influence cancer risk. Recently, a third SNP (SNP55C > T; rs2870820) was also reported to a...

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Detalles Bibliográficos
Autores principales: Helwa, Reham, Gansmo, Liv B., Romundstad, Pål, Hveem, Kristian, Vatten, Lars, Ryan, Bríd M., Harris, Curtis C., Lønning, Per E., Knappskog, Stian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022009/
https://www.ncbi.nlm.nih.gov/pubmed/27624283
http://dx.doi.org/10.1038/srep33153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022009/
https://www.ncbi.nlm.nih.gov/pubmed/27624283
http://dx.doi.org/10.1038/srep33153

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