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Mechanistic Modelling of DNA Repair and Cellular Survival Following Radiation-Induced DNA Damage

Characterising and predicting the effects of ionising radiation on cells remains challenging, with the lack of robust models of the underlying mechanism of radiation responses providing a significant limitation to the development of personalised radiotherapy. In this paper we present a mechanistic m...

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Detalles Bibliográficos
Autores principales: McMahon, Stephen J., Schuemann, Jan, Paganetti, Harald, Prise, Kevin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022028/
https://www.ncbi.nlm.nih.gov/pubmed/27624453
http://dx.doi.org/10.1038/srep33290