NAC selectively inhibit cancer telomerase activity: A higher redox homeostasis threshold exists in cancer cells

Telomerase activity controls telomere length, and this plays an important role in stem cells, aging and tumors. Antioxidant was shown to protect telomerase activity in normal cells but inhibit that in cancer cells, but the underlying mechanism is elusive. Here we found that 7721 hepatoma cells held...

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Detalles Bibliográficos
Autores principales: Li, Pengying, Wu, Meilin, Wang, Jing, Sui, Yilun, Liu, Shanlin, Shi, Dongyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022045/
https://www.ncbi.nlm.nih.gov/pubmed/26771767
http://dx.doi.org/10.1016/j.redox.2015.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022045/
https://www.ncbi.nlm.nih.gov/pubmed/26771767
http://dx.doi.org/10.1016/j.redox.2015.12.001

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