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Tempol improves xanthine oxidoreductase-mediated vascular responses to nitrite in experimental renovascular hypertension
Upregulation of xanthine oxidoreductase (XOR) increases vascular reactive oxygen species (ROS) levels and contributes to nitroso-redox imbalance. However, XOR can generate nitric oxide (NO) from nitrite, and increased superoxide could inactivate NO formed from nitrite. This study tested the hypothes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022046/ https://www.ncbi.nlm.nih.gov/pubmed/27078869 http://dx.doi.org/10.1016/j.redox.2016.04.001 |