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Tempol improves xanthine oxidoreductase-mediated vascular responses to nitrite in experimental renovascular hypertension

Upregulation of xanthine oxidoreductase (XOR) increases vascular reactive oxygen species (ROS) levels and contributes to nitroso-redox imbalance. However, XOR can generate nitric oxide (NO) from nitrite, and increased superoxide could inactivate NO formed from nitrite. This study tested the hypothes...

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Detalles Bibliográficos
Autores principales: Oliveira-Paula, Gustavo H., Pinheiro, Lucas C., Guimaraes, Danielle A., Tella, Sandra O. Conde, Blanco, Ana L. Furlan, Angelis, Celio D., Schechter, Alan N., Tanus-Santos, Jose E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022046/
https://www.ncbi.nlm.nih.gov/pubmed/27078869
http://dx.doi.org/10.1016/j.redox.2016.04.001