Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma()

BACKGROUND: Extensive cross talk exists between PI3K/Akt/mTOR and mitogen-activated protein kinase (MAPK) pathways, and both are upregulated in pancreatic ductal adenocarcinoma (PDAC). Our previous study suggested that epidermal growth factor receptor inhibitor erlotinib which acts upstream of these...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Matthew H., Xue, Aiqun, Baxter, Robert C., Pavlakis, Nick, Smith, Ross C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022074/
https://www.ncbi.nlm.nih.gov/pubmed/27435925
http://dx.doi.org/10.1016/j.neo.2016.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022074/
https://www.ncbi.nlm.nih.gov/pubmed/27435925
http://dx.doi.org/10.1016/j.neo.2016.06.001

Ejemplares similares