The structural basis of the dominant negative phenotype of the Gα(i1)β(1)γ(2) G203A/A326S heterotrimer

AIM: Dominant negative mutant G proteins have provided critical insight into the mechanisms of G protein-coupled receptor (GPCR) signaling, but the mechanisms underlying the dominant negative characteristics are not completely understood. The aim of this study was to determine the structure of the d...

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Detalles Bibliográficos
Autores principales: Liu, Ping, Jia, Ming-zhu, Zhou, X Edward, De Waal, Parker W, Dickson, Bradley M, Liu, Bo, Hou, Li, Yin, Yan-ting, Kang, Yan-yong, Shi, Yi, Melcher, Karsten, Xu, H Eric, Jiang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022103/
https://www.ncbi.nlm.nih.gov/pubmed/27498775
http://dx.doi.org/10.1038/aps.2016.69

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022103/
https://www.ncbi.nlm.nih.gov/pubmed/27498775
http://dx.doi.org/10.1038/aps.2016.69

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