Lipid Nanoparticle-mediated siRNA Transfer Against PCTAIRE1/PCTK1/Cdk16 Inhibits In Vivo Cancer Growth

PCTAIRE1/CDK16/PCTK1 plays critical roles in cancer cell proliferation and antiapoptosis. To advance our previously published in vitro results with PCTAIRE1 silencing, we examined the in vivo therapeutic potential of this approach by using small interfering RNA (siRNA) encapsulated by lipid nanopart...

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Detalles Bibliográficos
Autores principales: Yanagi, Teruki, Tachikawa, Kiyoshi, Wilkie-Grantham, Rachel, Hishiki, Asami, Nagai, Ko, Toyonaga, Ellen, Chivukula, Pad, Matsuzawa, Shu-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022131/
https://www.ncbi.nlm.nih.gov/pubmed/27351680
http://dx.doi.org/10.1038/mtna.2016.40

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022131/
https://www.ncbi.nlm.nih.gov/pubmed/27351680
http://dx.doi.org/10.1038/mtna.2016.40

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