Long-term treatment with metformin in obese, insulin-resistant adolescents: results of a randomized double-blinded placebo-controlled trial

BACKGROUND: As adolescents with obesity and insulin resistance may be refractory to lifestyle intervention therapy alone, additional off-label metformin therapy is often used. In this study, the long-term efficacy and safety of metformin versus placebo in adolescents with obesity and insulin resista...

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Detalles Bibliográficos
Autores principales: van der Aa, M P, Elst, M A J, van de Garde, E M W, van Mil, E G A H, Knibbe, C A J, van der Vorst, M M J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022149/
https://www.ncbi.nlm.nih.gov/pubmed/27571249
http://dx.doi.org/10.1038/nutd.2016.37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022149/
https://www.ncbi.nlm.nih.gov/pubmed/27571249
http://dx.doi.org/10.1038/nutd.2016.37

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