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Molecular Pap smear: HPV genotype and DNA methylation of ADCY8, CDH8, and ZNF582 as an integrated biomarker for high-grade cervical cytology

BACKGROUND: The Pap smear has remained the foundation for cervical cancer screening for over 70 years. With advancements in molecular diagnostics, primary high-risk human papillomavirus (hrHPV) screening has recently become an accepted stand-alone or co-test with conventional cytology. However, both...

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Detalles Bibliográficos
Autores principales: Shen-Gunther, Jane, Wang, Chiou-Miin, Poage, Graham M., Lin, Chun-Lin, Perez, Luis, Banks, Nancy A., Huang, Tim Hui-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022163/
https://www.ncbi.nlm.nih.gov/pubmed/27651839
http://dx.doi.org/10.1186/s13148-016-0263-9