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WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition

BACKGROUND: WNT5A (-/-) mammary tissue has been shown to exhibit increased ductal elongation, suggesting elevated mammary cell migration. Increased epithelial cell migration/invasion has often but not always been linked to the epithelial-mesenchymal transition (EMT). In the current study, we investi...

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Detalles Bibliográficos
Autores principales: Prasad, Chandra Prakash, Chaurasiya, Shivendra Kumar, Guilmain, William, Andersson, Tommy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022188/
https://www.ncbi.nlm.nih.gov/pubmed/27623766
http://dx.doi.org/10.1186/s13046-016-0421-0