Immunoseq: the identification of functionally relevant variants through targeted capture and sequencing of active regulatory regions in human immune cells

BACKGROUND: The observation that the genetic variants identified in genome-wide association studies (GWAS) frequently lie in non-coding regions of the genome that contain cis-regulatory elements suggests that altered gene expression underlies the development of many complex traits. In order to effic...

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Detalles Bibliográficos
Autores principales: Morin, Andréanne, Kwan, Tony, Ge, Bing, Letourneau, Louis, Ban, Maria, Tandre, Karolina, Caron, Maxime, Sandling, Johanna K., Carlsson, Jonas, Bourque, Guillaume, Laprise, Catherine, Montpetit, Alexandre, Syvanen, Ann-Christine, Ronnblom, Lars, Sawcer, Stephen J., Lathrop, Mark G., Pastinen, Tomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022205/
https://www.ncbi.nlm.nih.gov/pubmed/27624058
http://dx.doi.org/10.1186/s12920-016-0220-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022205/
https://www.ncbi.nlm.nih.gov/pubmed/27624058
http://dx.doi.org/10.1186/s12920-016-0220-7

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