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Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk

OBJECTIVE: We sought to estimate the causal effect of low serum 25(OH)D on multiple sclerosis (MS) susceptibility that is not confounded by environmental or lifestyle factors or subject to reverse causality. METHODS: We conducted mendelian randomization (MR) analyses using an instrumental variable (...

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Detalles Bibliográficos
Autores principales: Rhead, Brooke, Bäärnhielm, Maria, Gianfrancesco, Milena, Mok, Amanda, Shao, Xiaorong, Quach, Hong, Shen, Ling, Schaefer, Catherine, Link, Jenny, Gyllenberg, Alexandra, Hedström, Anna Karin, Olsson, Tomas, Hillert, Jan, Kockum, Ingrid, Glymour, M. Maria, Alfredsson, Lars, Barcellos, Lisa F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022843/
https://www.ncbi.nlm.nih.gov/pubmed/27652346
http://dx.doi.org/10.1212/NXG.0000000000000097