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Membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia

Bile acids are potential carcinogens in gastrointestinal cancer, and interact with nuclear and membrane receptors to initiate downstream signaling. The effect of TGR5 [also known as G protein-coupled bile acid receptor 1 (GPBAR1)] on cancer progression is dependent on the tissue where it is activate...

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Detalles Bibliográficos
Autores principales: Chen, Min-Chan, Chen, Yi-Ling, Wang, Tzu-Wen, Hsu, Hui-Ping, Lai, Ming-Derg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022870/
https://www.ncbi.nlm.nih.gov/pubmed/27510297
http://dx.doi.org/10.3892/or.2016.5011