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PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTEN

Peritoneal metastasis is the most frequent cause of death in patients with advanced gastric carcinoma (GC). The phosphatase of regenerating liver-3 (PRL-3) is recognized as an oncogene and plays an important role in GC peritoneal metastasis. However, the mechanism of how PRL-3 regulates GC invasion...

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Detalles Bibliográficos
Autores principales: Xiong, Jianbo, Li, Zhengrong, Zhang, Yang, Li, Daojiang, Zhang, Guoyang, Luo, Xianshi, Jie, Zhigang, Liu, Yi, Cao, Yi, Le, Zhibiao, Tan, Shengxing, Zou, Wenyu, Gong, Peitao, Qiu, Lingyu, Li, Yuanyuan, Wang, Huan, Chen, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022899/
https://www.ncbi.nlm.nih.gov/pubmed/27572739
http://dx.doi.org/10.3892/or.2016.5030