Cargando…

Combination of the histone deacetylase inhibitor depsipeptide and 5-fluorouracil upregulates major histocompatibility complex class II and p21 genes and activates caspase-3/7 in human colon cancer HCT-116 cells

Epigenetic anticancer drugs such as histone deacetylase (HDAC) inhibitors have been combined with existing anticancer drugs for synergistic or additive effects. In the present study, we found that a very low concentration of depsipeptide, an HDAC inhibitor, potentiated the antitumor activity of 5-fl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okada, Kouji, Hakata, Shuko, Terashima, Jun, Gamou, Toshie, Habano, Wataru, Ozawa, Shogo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022900/ https://www.ncbi.nlm.nih.gov/pubmed/27509880 http://dx.doi.org/10.3892/or.2016.5008

Ejemplares similares

Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells
por: Habano, Wataru, et al.
Publicado: (2011)

Cellular irinotecan resistance in colorectal cancer and overcoming irinotecan refractoriness through various combination trials including DNA methyltransferase inhibitors: a review
por: Ozawa, Shogo, et al.
Publicado: (2021)

Prunus spinosa Extract Sensitized HCT116 Spheroids to 5-Fluorouracil Toxicity, Inhibiting Autophagy
por: Condello, Maria, et al.
Publicado: (2022)

An aryl hydrocarbon receptor induces VEGF expression through ATF4 under glucose deprivation in HepG2
por: Terashima, Jun, et al.
Publicado: (2013)

β-naphthoflavone-induced upregulation of CYP1B1 expression is mediated by the preferential binding of aryl hydrocarbon receptor to unmethylated xenobiotic responsive elements
por: Miura, Toshitaka, et al.
Publicado: (2021)

Comparison of gene expression in HCT116 treatment derivatives generated by two different 5-fluorouracil exposure protocols
por: De Angelis, Paula M, et al.
Publicado: (2004)

A ruthenium-based 5-fluorouracil complex with enhanced cytotoxicity and apoptosis induction action in HCT116 cells
por: Silva, Valdenizia Rodrigues, et al.
Publicado: (2018)

Molecular Mechanisms and Tumor Biological Aspects of 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells
por: Kurasaka, Chinatsu, et al.
Publicado: (2021)

Ethanolic extract of Brucea javanica inhibit proliferation of HCT-116 colon cancer cells via caspase activation
por: Bagheri, E., et al.
Publicado: (2018)

Analysis of DNA methylation landscape reveals the roles of DNA methylation in the regulation of drug metabolizing enzymes
por: Habano, Wataru, et al.
Publicado: (2015)

Relationship between anticancer sensitivities and cellular respiration properties in 5‐fluorouracil‐resistant HCT116 human colorectal cancer cells
por: Kurasaka, Chinatsu, et al.
Publicado: (2023)

5-Fluorouracil Induce the Expression of TLR4 on HCT116 Colorectal Cancer Cell Line Expressing Different Variants of TLR4
por: Davoodi, Homa, et al.
Publicado: (2013)

Coptidis Rhizoma Extract Reverses 5-Fluorouracil Resistance in HCT116 Human Colorectal Cancer Cells via Modulation of Thymidylate Synthase
por: Kang, Yong-Hwi, et al.
Publicado: (2021)

Anti-Cancer Effects of Zotarolimus Combined with 5-Fluorouracil Treatment in HCT-116 Colorectal Cancer-Bearing BALB/c Nude Mice
por: Chang, Geng-Ruei, et al.
Publicado: (2021)

Metformin Induces a Caspase 3-Unrelated Apoptosis in Human Colorectal Cancer Cell Lines HCT116 and SW620
por: Rosidi, Bustanur, et al.
Publicado: (2023)

Intra-Tumoral Heterogeneity in Metastatic Potential and Survival Signaling between Iso-Clonal HCT116 and HCT116b Human Colon Carcinoma Cell Lines
por: Chowdhury, Sanjib, et al.
Publicado: (2013)

The effect of noisome preparation methods in encapsulating 5-fluorouracil and real time cell assay against HCT-116 colon cancer cell line
por: Ugorji, Onyinyechi Lydia, et al.
Publicado: (2022)

Effect of AKT3 expression on MYC‐ and caspase‐8‐dependent apoptosis caused by polo‐like kinase inhibitors in HCT 116 cells
por: Nonomiya, Yuma, et al.
Publicado: (2016)

[Corrigendum] Effects of histone deacetylase inhibitors on ATP‑binding cassette transporters in lung cancer A549 and colorectal cancer HCT116 cells
por: Wang, Hao, et al.
Publicado: (2023)

Resistin and Visfatin Expression in HCT-116 Colorectal Cancer Cell Line
por: Ghaemmaghami, Sara, et al.
Publicado: (2013)

Characterization of sphere-forming HCT116 clones by whole RNA sequencing
por: Chung, Eunkyung, et al.
Publicado: (2016)

Procaine Induces Epigenetic Changes in HCT116 Colon Cancer Cells
por: Sabit, Hussein, et al.
Publicado: (2016)

Entrainment of superoxide rhythm by menadione in HCT116 colon cancer cells
por: Kizhuveetil, Uma, et al.
Publicado: (2019)

A delay prior to mitotic entry triggers caspase 8-dependent cell death in p53-deficient Hela and HCT-116 cells
por: Silva, Victoria C, et al.
Publicado: (2015)

ROS-induced cleavage of NHLRC2 by caspase-8 leads to apoptotic cell death in the HCT116 human colon cancer cell line
por: Nishi, Kensuke, et al.
Publicado: (2017)

Antichemosensitizing effect of resveratrol in cotreatment with oxaliplatin in HCT116 colon cancer cell
por: Park, Dong-Guk
Publicado: (2014)

Carvacrol alters soluble factors in HCT-116 and HT-29 cell lines
por: PAKDEMİRLİ, Ahu, et al.
Publicado: (2020)

Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo
por: Huang, Han-Lin, et al.
Publicado: (2012)

Effect of AICAR and 5-Fluorouracil on X-ray Repair, Cross-Complementing Group 1 Expression, and Consequent Cytotoxicity Regulation in Human HCT-116 Colorectal Cancer Cells
por: Lee, Ko-Chao, et al.
Publicado: (2017)

Correction: Anticancer Activity of MPT0E028, a Novel Potent Histone Deacetylase Inhibitor, in Human Colorectal Cancer HCT116 Cells In Vitro and In Vivo
por: Huang, Han-Li, et al.
Publicado: (2012)

Low Dose Histone Deacetylase Inhibitor, Depsipeptide (FR901228), Promotes Adenoviral Transduction in Human Rhabdomyosarcoma Cell Lines
por: Navid, Fariba, et al.
Publicado: (2004)

Antitumor activity and pharmacologic characterization of the depsipeptide analog as a novel histone deacetylase/ phosphatidylinositol 3‐kinase dual inhibitor
por: Saijo, Ken, et al.
Publicado: (2017)

Change in Expression of Survivin Caused by Using Oxaliplatin in HCT116 Colon Cancer Cells
por: Sohn, Won Jun, et al.
Publicado: (2010)

In situ Proteomic Profiling of Curcumin Targets in HCT116 Colon Cancer Cell Line
por: Wang, Jigang, et al.
Publicado: (2016)

Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells
por: Zhao, Lv-Cui, et al.
Publicado: (2015)

DZNep inhibits the proliferation of colon cancer HCT116 cells by inducing senescence and apoptosis
por: Sha, Mingquan, et al.
Publicado: (2015)

Methylsulfonylmethane Induces p53 Independent Apoptosis in HCT-116 Colon Cancer Cells
por: Karabay, Arzu Zeynep, et al.
Publicado: (2016)

Zerumbone reduces proliferation of HCT116 colon cancer cells by inhibition of TNF-alpha
por: Singh, Salam Pradeep, et al.
Publicado: (2018)

Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116
por: Myung, Jae Kyung, et al.
Publicado: (2016)

In vivo anticancer activity of a rhodium metalloinsertor in the HCT116 xenograft tumor model
por: Threatt, Stephanie D., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dsq78sbn0vtg0mn3qria8m9pb6