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Crosstalk between Beclin-1-dependent autophagy and caspase-dependent apoptosis induced by tanshinone IIA in human osteosarcoma MG-63 cells

The aim of the present study was to ascertain whether or not autophagy is induced by tanshinone IIA (TanIIA), and to explore the crosstalk between autophagy and apoptosis in regards to the antitumor effects of TanIIA on MG-63 cells and the potential mechanism. MG-63 cells were cultured in vitro with...

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Detalles Bibliográficos
Autores principales: Ma, Kun, Zhang, Chuan, Huang, Man-Yu, Guo, Yan-Xing, Hu, Guo-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022923/
https://www.ncbi.nlm.nih.gov/pubmed/27499329
http://dx.doi.org/10.3892/or.2016.5003