PERK Regulates Working Memory and Protein Synthesis-Dependent Memory Flexibility

PERK (EIF2AK3) is an ER-resident eIF2α kinase required for memory flexibility and metabotropic glutamate receptor-dependent long-term depression, processes known to be dependent on new protein synthesis. Here we investigated PERK’s role in working memory, a cognitive ability that is independent of n...

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Detalles Bibliográficos
Autores principales: Zhu, Siying, Henninger, Keely, McGrath, Barbara C., Cavener, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023101/
https://www.ncbi.nlm.nih.gov/pubmed/27627766
http://dx.doi.org/10.1371/journal.pone.0162766

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023101/
https://www.ncbi.nlm.nih.gov/pubmed/27627766
http://dx.doi.org/10.1371/journal.pone.0162766

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