The Rheumatoid Arthritis Risk Variant CCR6DNP Regulates CCR6 via PARP-1

Understanding the implications of genome-wide association studies (GWAS) for disease biology requires both identification of causal variants and definition of how these variants alter gene function. The non-coding triallelic dinucleotide polymorphism CCR6DNP is associated with risk for rheumatoid ar...

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Detalles Bibliográficos
Autores principales: Li, Gang, Cunin, Pierre, Wu, Di, Diogo, Dorothée, Yang, Yu, Okada, Yukinori, Plenge, Robert M., Nigrovic, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023119/
https://www.ncbi.nlm.nih.gov/pubmed/27626929
http://dx.doi.org/10.1371/journal.pgen.1006292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023119/
https://www.ncbi.nlm.nih.gov/pubmed/27626929
http://dx.doi.org/10.1371/journal.pgen.1006292

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