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Evaluating Tissue-Specific Recombination in a Pdgfrα-CreER(T2) Transgenic Mouse Line

In the central nervous system (CNS) platelet derived growth factor receptor alpha (PDGFRα) is expressed exclusively by oligodendrocyte progenitor cells (OPCs), making the Pdgfrα promoter an ideal tool for directing transgene expression in this cell type. Two Pdgfrα-CreER(T2) mouse lines have been ge...

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Detalles Bibliográficos
Autores principales: O’Rourke, Megan, Cullen, Carlie L., Auderset, Loic, Pitman, Kimberley A., Achatz, Daniela, Gasperini, Robert, Young, Kaylene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023134/
https://www.ncbi.nlm.nih.gov/pubmed/27626928
http://dx.doi.org/10.1371/journal.pone.0162858