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A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion

Salmonella Typhimurium (S. Tm) is a leading cause of diarrhea. The disease is triggered by pathogen invasion into the gut epithelium. Invasion is attributed to the SPI-1 type 3 secretion system (T1). T1 injects effector proteins into epithelial cells and thereby elicits rearrangements of the host ce...

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Detalles Bibliográficos
Autores principales: Andritschke, Daniel, Dilling, Sabrina, Emmenlauer, Mario, Welz, Tobias, Schmich, Fabian, Misselwitz, Benjamin, Rämö, Pauli, Rottner, Klemens, Kerkhoff, Eugen, Wada, Teiji, Penninger, Josef M., Beerenwinkel, Niko, Horvath, Peter, Dehio, Christoph, Hardt, Wolf-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023170/
https://www.ncbi.nlm.nih.gov/pubmed/27627128
http://dx.doi.org/10.1371/journal.pone.0161965