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A Cytokine Signalling Network for the Regulation of Inducible Nitric Oxide Synthase Expression in Rheumatoid Arthritis

In rheumatoid arthritis (RA), nitric oxide (NO) is implicated in inflammation, angiogenesis and tissue destruction. The enzyme inducible nitric oxide synthase (iNOS) is responsible for the localised over-production of NO in the synovial joints affected by RA. The pro- and anti-inflammatory cytokines...

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Detalles Bibliográficos
Autores principales: Dey, Poulami, Panga, Venugopal, Raghunathan, Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023176/
https://www.ncbi.nlm.nih.gov/pubmed/27626941
http://dx.doi.org/10.1371/journal.pone.0161306