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Long Non-coding RNA BGas Regulates the Cystic Fibrosis Transmembrane Conductance Regulator

Cystic fibrosis (CF) is a life-shortening genetic disease. The root cause of CF is heritable recessive mutations that affect the cystic fibrosis transmembrance conductance regulator (CFTR) gene and the subsequent expression and activity of encoded ion channels at the cell surface. We show that CFTR...

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Detalles Bibliográficos
Autores principales: Saayman, Sheena M, Ackley, Amanda, Burdach, Jon, Clemson, Matthew, Gruenert, Dieter C, Tachikawa, Kiyoshi, Chivukula, Pad, Weinberg, Marc S, Morris, Kevin V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023374/
https://www.ncbi.nlm.nih.gov/pubmed/27434588
http://dx.doi.org/10.1038/mt.2016.112