Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice

A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated for the delivery of antisense oligonuclotides (AOs), 2′-O-methyl phosphorothioate RNA (2′-OMePS) and phosphorodiamidate morpholino oligomer (PMO) in cell culture and dystro...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Mingxing, Wu, Bo, Tucker, Jason D, Bollinger, Lauren E, Lu, Peijuan, Lu, Qilong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023397/
https://www.ncbi.nlm.nih.gov/pubmed/27483024
http://dx.doi.org/10.1038/mtna.2016.51

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023397/
https://www.ncbi.nlm.nih.gov/pubmed/27483024
http://dx.doi.org/10.1038/mtna.2016.51

Ejemplares similares