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Poly(ester amine) Composed of Polyethylenimine and Pluronic Enhance Delivery of Antisense Oligonucleotides In Vitro and in Dystrophic mdx Mice

A series of poly(esteramine)s (PEAs) constructed from low molecular weight polyethyleneimine (LPEI) and Pluronic were evaluated for the delivery of antisense oligonuclotides (AOs), 2′-O-methyl phosphorothioate RNA (2′-OMePS) and phosphorodiamidate morpholino oligomer (PMO) in cell culture and dystro...

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Detalles Bibliográficos
Autores principales:	Wang, Mingxing, Wu, Bo, Tucker, Jason D, Bollinger, Lauren E, Lu, Peijuan, Lu, Qilong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023397/ https://www.ncbi.nlm.nih.gov/pubmed/27483024 http://dx.doi.org/10.1038/mtna.2016.51

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