Nucleolin-aptamer therapy in retinoblastoma: molecular changes and mass spectrometry–based imaging

Retinoblastoma (RB) is an intraocular childhood tumor which, if left untreated, leads to blindness and mortality. Nucleolin (NCL) protein which is differentially expressed on the tumor cell surface, binds ligands and regulates carcinogenesis and angiogenesis. We found that NCL is over expressed in R...

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Detalles Bibliográficos
Autores principales: Subramanian, Nithya, Srimany, Amitava, Kanwar, Jagat R, Kanwar, Rupinder K, Akilandeswari, Balachandran, Rishi, Pukhraj, Khetan, Vikas, Vasudevan, Madavan, Pradeep, Thalappil, Krishnakumar, Subramanian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023409/
https://www.ncbi.nlm.nih.gov/pubmed/27574784
http://dx.doi.org/10.1038/mtna.2016.70

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023409/
https://www.ncbi.nlm.nih.gov/pubmed/27574784
http://dx.doi.org/10.1038/mtna.2016.70

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