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Structural insights into the molecular mechanism of the m(6)A writer complex

Methylation of adenosines at the N(6) position (m(6)A) is a dynamic and abundant epitranscriptomic mark that regulates critical aspects of eukaryotic RNA metabolism in numerous biological processes. The RNA methyltransferases METTL3 and METTL14 are components of a multisubunit m(6)A writer complex w...

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Detalles Bibliográficos
Autores principales: Śledź, Paweł, Jinek, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023411/
https://www.ncbi.nlm.nih.gov/pubmed/27627798
http://dx.doi.org/10.7554/eLife.18434