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Analysis of compound heterozygotes reveals that the mouse floxed Pax6(tm1Ued) allele produces abnormal eye phenotypes

Analysis of abnormal phenotypes produced by different types of mutations has been crucial for our understanding of gene function. Some floxed alleles that retain a neomycin-resistance selection cassette (neo cassette) are not equivalent to wild-type alleles and provide useful experimental resources....

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Detalles Bibliográficos
Autores principales: Dorà, Natalie J., Crookshanks, Aaron J. F., Leung, Karen K. Y., Simpson, T. Ian, Mason, John O., Price, David J., West, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023747/
https://www.ncbi.nlm.nih.gov/pubmed/27240603
http://dx.doi.org/10.1007/s11248-016-9962-4