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Analysis of compound heterozygotes reveals that the mouse floxed Pax6(tm1Ued) allele produces abnormal eye phenotypes
Analysis of abnormal phenotypes produced by different types of mutations has been crucial for our understanding of gene function. Some floxed alleles that retain a neomycin-resistance selection cassette (neo cassette) are not equivalent to wild-type alleles and provide useful experimental resources....
Autores principales: | Dorà, Natalie J., Crookshanks, Aaron J. F., Leung, Karen K. Y., Simpson, T. Ian, Mason, John O., Price, David J., West, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023747/ https://www.ncbi.nlm.nih.gov/pubmed/27240603 http://dx.doi.org/10.1007/s11248-016-9962-4 |
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