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The dopamine D(2) receptor dimer and its interaction with homobivalent antagonists: homology modeling, docking and molecular dynamics
In order to apply structure-based drug design techniques to G protein-coupled receptor complexes, it is essential to model their 3D structure and to identify regions that are suitable for selective drug binding. For this purpose, we have developed and tested a multi-component protocol to model the i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023759/ https://www.ncbi.nlm.nih.gov/pubmed/27491852 http://dx.doi.org/10.1007/s00894-016-3065-2 |