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An investigation of the association of genetic susceptibility risk with somatic mutation burden in breast cancer

BACKGROUND: Genome-wide association studies have reported nearly 100 common germline susceptibility loci associated with the risk for breast cancer. Tumour sequencing studies have characterised somatic mutation profiles in breast cancer patients. The relationship between breast cancer susceptibility...

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Detalles Bibliográficos
Autores principales: Zhu, Bin, Mukherjee, Anwesha, Machiela, Mitchell J, Song, Lei, Hua, Xing, Shi, Jianxin, Garcia-Closas, Montserrat, Chanock, Stephen J, Chatterjee, Nilanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023771/
https://www.ncbi.nlm.nih.gov/pubmed/27467053
http://dx.doi.org/10.1038/bjc.2016.223