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A Comparison of Classical and H-Type Bovine Spongiform Encephalopathy Associated with E211K Prion Protein Polymorphism in Wild-Type and EK211 Cattle Following Intracranial Inoculation

In 2006, a case of H-type bovine spongiform encephalopathy (BSE-H) was diagnosed in a cow that was associated with a heritable polymorphism in the bovine prion protein gene (PRNP) resulting in a lysine for glutamate amino acid substitution at codon 211 (called E211K) of the prion protein. Although t...

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Detalles Bibliográficos
Autores principales: Moore, S. Jo, West Greenlee, M. Heather, Smith, Jodi D., Vrentas, Catherine E., Nicholson, Eric M., Greenlee, Justin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023952/
https://www.ncbi.nlm.nih.gov/pubmed/27695695
http://dx.doi.org/10.3389/fvets.2016.00078