High cell-surface density of HER2 deforms cell membranes

Breast cancers (BC) with HER2 overexpression (referred to as HER2 positive) progress more aggressively than those with normal expression. Targeted therapies against HER2 can successfully delay the progression of HER2-positive BC, but details of how this overexpression drives the disease are not full...

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Detalles Bibliográficos
Autores principales: Chung, Inhee, Reichelt, Mike, Shao, Lily, Akita, Robert W., Koeppen, Hartmut, Rangell, Linda, Schaefer, Gabriele, Mellman, Ira, Sliwkowski, Mark X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023959/
https://www.ncbi.nlm.nih.gov/pubmed/27599456
http://dx.doi.org/10.1038/ncomms12742

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5023959/
https://www.ncbi.nlm.nih.gov/pubmed/27599456
http://dx.doi.org/10.1038/ncomms12742

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