Six1 is down‐regulated in end‐stage human dilated cardiomyopathy independently of Ezh2

BACKGROUND: Recently, it was shown that a knock‐out (KO) of the polycomb histone methyltransferase Ezh2 leads to cardiac hypertrophy in mice, which was driven by the homeodomain transcription factor Six1. Here, we analyzed the expression of Six1 and its regulating factor Ezh2 in cardiac tissue of pa...

Descripción completa

Detalles Bibliográficos
Autores principales: Tschirner, Anika, Palus, Sandra, Hetzer, Roland, Meyer, Rudolf, Anker, Stefan D., Springer, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024036/
https://www.ncbi.nlm.nih.gov/pubmed/27668088
http://dx.doi.org/10.1002/ehf2.12017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024036/
https://www.ncbi.nlm.nih.gov/pubmed/27668088
http://dx.doi.org/10.1002/ehf2.12017

Ejemplares similares