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Six1 is down‐regulated in end‐stage human dilated cardiomyopathy independently of Ezh2
BACKGROUND: Recently, it was shown that a knock‐out (KO) of the polycomb histone methyltransferase Ezh2 leads to cardiac hypertrophy in mice, which was driven by the homeodomain transcription factor Six1. Here, we analyzed the expression of Six1 and its regulating factor Ezh2 in cardiac tissue of pa...
Autores principales: | Tschirner, Anika, Palus, Sandra, Hetzer, Roland, Meyer, Rudolf, Anker, Stefan D., Springer, Jochen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024036/ https://www.ncbi.nlm.nih.gov/pubmed/27668088 http://dx.doi.org/10.1002/ehf2.12017 |
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