Amyloid structure exhibits polymorphism on multiple length scales in human brain tissue

Aggregation of Aβ amyloid fibrils into plaques in the brain is a universal hallmark of Alzheimer’s Disease (AD), but whether plaques in different individuals are equivalent is unknown. One possibility is that amyloid fibrils exhibit different structures and different structures may contribute differ...

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Detalles Bibliográficos
Autores principales: Liu, Jiliang, Costantino, Isabel, Venugopalan, Nagarajan, Fischetti, Robert F., Hyman, Bradley T., Frosch, Matthew P., Gomez-Isla, Teresa, Makowski, Lee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024092/
https://www.ncbi.nlm.nih.gov/pubmed/27629394
http://dx.doi.org/10.1038/srep33079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024092/
https://www.ncbi.nlm.nih.gov/pubmed/27629394
http://dx.doi.org/10.1038/srep33079

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