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Diagnostic copper imaging of Menkes disease by synchrotron radiation-generated X-ray fluorescence analysis
Copper (Cu) is an indispensable metal for normal development and function of humans, especially in central nervous system (CNS). However, its redox activity requires accurate Cu transport system. ATP7A, a main Cu(2+) transporting-ATPase, is necessary to efflux Cu across the plasma membrane and synth...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024095/ https://www.ncbi.nlm.nih.gov/pubmed/27629586 http://dx.doi.org/10.1038/srep33247 |