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Diagnostic copper imaging of Menkes disease by synchrotron radiation-generated X-ray fluorescence analysis

Copper (Cu) is an indispensable metal for normal development and function of humans, especially in central nervous system (CNS). However, its redox activity requires accurate Cu transport system. ATP7A, a main Cu(2+) transporting-ATPase, is necessary to efflux Cu across the plasma membrane and synth...

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Detalles Bibliográficos
Autores principales: Kinebuchi, Miyuki, Matsuura, Akihiro, Kiyono, Tohru, Nomura, Yumiko, Kimura, Sachiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024095/
https://www.ncbi.nlm.nih.gov/pubmed/27629586
http://dx.doi.org/10.1038/srep33247