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STYK1 promotes epithelial-mesenchymal transition and tumor metastasis in human hepatocellular carcinoma through MEK/ERK and PI3K/AKT signaling

Serine/threonine/tyrosine kinase 1 (STYK1) is known to be involved in tumor progression. However, its molecular role and mechanism in hepatocellular carcinoma (HCC) remains unknown. We evaluated the effect of STYK1 expression in HCC tissues and investigated the underlying mechanisms associated with...

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Detalles Bibliográficos
Autores principales: Wang, Zhaowen, Qu, Lei, Deng, Biao, Sun, Xing, Wu, Shaohan, Liao, Jianhua, Fan, Junwei, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024114/
https://www.ncbi.nlm.nih.gov/pubmed/27628214
http://dx.doi.org/10.1038/srep33205