Long-term adaptation of the influenza A virus by escaping cytotoxic T-cell recognition

The evolutionary adaptation of the influenza A virus (IAV) to human antibodies is well characterised. Much less is known about the long-term evolution of cytotoxic T lymphocyte (CTL) epitopes, which are important antigens for clearance of infection. We construct an antigenic map of IAVs of all human...

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Detalles Bibliográficos
Autores principales: Woolthuis, Rutger G., van Dorp, Christiaan H., Keşmir, Can, de Boer, Rob J., van Boven, Michiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024124/
https://www.ncbi.nlm.nih.gov/pubmed/27629812
http://dx.doi.org/10.1038/srep33334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024124/
https://www.ncbi.nlm.nih.gov/pubmed/27629812
http://dx.doi.org/10.1038/srep33334

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