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Prolyl-isomerase Pin1 controls Notch3 protein expression and regulates T-ALL progression

Deregulated Notch signaling is associated with T-cell Acute Lymphoblastic Leukemia (T-ALL) development and progression. Increasing evidence reveals that Notch pathway has an important role in the invasion ability of tumor cells, including leukemia, although the underlying molecular mechanisms remain...

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Detalles Bibliográficos
Autores principales: Franciosa, G, Diluvio, G, Gaudio, F Del, Giuli, M V, Palermo, R, Grazioli, P, Campese, A F, Talora, C, Bellavia, D, D'Amati, G, Besharat, Z M, Nicoletti, C, Siebel, C W, Choy, L, Rustighi, A, Sal, G Del, Screpanti, I, Checquolo, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024153/
https://www.ncbi.nlm.nih.gov/pubmed/26876201
http://dx.doi.org/10.1038/onc.2016.5