HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome

In cervical squamous cell carcinomas, high-risk human papillomavirus (HRHPV) DNA is usually integrated into host chromosomes. Multiple integration events are thought to be present within the cells of a polyclonal premalignant lesion and the features that underpin clonal selection of one particular i...

Descripción completa

Detalles Bibliográficos
Autores principales: Groves, I J, Knight, E L A, Ang, Q Y, Scarpini, C G, Coleman, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024154/
https://www.ncbi.nlm.nih.gov/pubmed/26876196
http://dx.doi.org/10.1038/onc.2016.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024154/
https://www.ncbi.nlm.nih.gov/pubmed/26876196
http://dx.doi.org/10.1038/onc.2016.8

Ejemplares similares