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Chiral PCB 91 and 149 Toxicity Testing in Embryo and Larvae (Danio rerio): Application of Targeted Metabolomics via UPLC-MS/MS

In this study, we aimed to investigate the dysfunction of zebrafish embryos and larvae induced by rac-/(+)-/(−)- PCB91 and rac-/(−)-/(+)- PCB149. UPLC-MS/MS (Ultra-performance liquid chromatography coupled with mass spectrometry) was employed to perform targeted metabolomics analysis, including the...

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Detalles Bibliográficos
Autores principales: Chai, Tingting, Cui, Feng, Yin, Zhiqiang, Yang, Yang, Qiu, Jing, Wang, Chengju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024159/
https://www.ncbi.nlm.nih.gov/pubmed/27629264
http://dx.doi.org/10.1038/srep33481